Description
Stigamet Tablet – Type 2 Diabetes in Pakistan | Caliph Pharma
Stigamet Tablet is a fixed-dose combination tablet produced by Caliph Pharma that contains Sitagliptin 50mg and Metformin 500mg, designed for adult patients with type 2 diabetes mellitus in Pakistan. This combination supports improved glycemic control through two complementary mechanisms—enhancing insulin response and reducing hepatic glucose production—when diet and exercise alone are not sufficient.
Uses / Indications
The combination of Sitagliptin and Metformin (50mg/500mg) is indicated for the treatment of type 2 diabetes mellitus in adults:
as adjunct to diet and exercise when metformin alone or sitagliptin alone does not provide adequate glycemic control.
as replacement of both components when appropriate and as directed by a physician.
How It Works
Sitagliptin: A DPP-4 inhibitor that increases active incretin hormones (GLP-1 and GIP) which enhance insulin secretion and reduce glucagon release in a glucose-dependent manner.
Metformin: A biguanide that decreases hepatic glucose production, reduces intestinal absorption of glucose, and improves insulin sensitivity peripherally.
The dual combination results in improved fasting and post-meal glucose control, helping to lower HbA₁c when used alongside diet and exercise.
Product Details
Brand Name: Stigamet Tablet
Generic Name: Sitagliptin 50mg + Metformin 500mg
Therapeutic Class: DPP-4 Inhibitor + Biguanide (Dual Antidiabetic Combination)
Dosage Form: Film-Coated Tablet
Strength: Sitagliptin 50mg + Metformin 500mg
Package Size: 14’s
Storage Condition: Store below 30 °C; keep dry and tightly closed in original blister/pack; protect from moisture.
Manufacturer: Caliph Pharma (Pvt.) Ltd.
FAQ
What is Stigamet Tablet used for?
It’s used to treat adults with type 2 diabetes when diet and exercise alone don’t provide adequate blood sugar control, by combining Sitagliptin and Metformin in a single tablet.
When should I take Stigamet Tablet?
Typically once daily with breakfast (or as per your doctor) to improve tolerability and glucose control.
Can I stop taking other diabetes medicines when I start Stigamet Tablet?
Only under your physician’s guidance — your doctor will decide whether to replace or add medications based on your individual response and condition.
What happens if I miss a dose?
Take the missed dose as soon as you remember unless it’s near the time of your next dose. Do not double the dose.
Will this help reduce my HbA₁c?
Yes — this dual combination helps improve both fasting and post-meal glucose levels, supporting reduction of HbA₁c when used consistently with diet and exercise.
Additional information
| Generic Composition | Sitagliptin 50mg + Metformin 500mg |
|---|---|
| Pack Size | 14`s |

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