Description
Stigamet DS Tablet – Sitagliptin + Metformin for Type 2 Diabetes in Pakistan | Caliph Pharma
Stigamet DS Tablet is a fixed-dose combination tablet by Caliph Pharma containing Sitagliptin 50mg and Metformin 1000mg, developed for adult patients with type 2 diabetes mellitus in Pakistan. This dual-therapy helps improve glycemic control by enhancing insulin response and reducing hepatic glucose production when diet and exercise alone are insufficient.
Uses / Indications
Sitagliptin-Metformin combination (50mg/1000mg) is indicated for the treatment of type 2 diabetes mellitus in adults:
as adjunct to diet and exercise in patients already on metformin who require additional glycemic control,
or as replacement of both components when appropriate.
How It Works
Sitagliptin: a DPP-4 inhibitor that increases active incretin levels (GLP-1 & GIP), thus increasing insulin release and decreasing glucagon levels in a glucose-dependent manner.
Metformin: a biguanide which reduces hepatic glucose production, improves insulin sensitivity, and enhances peripheral glucose uptake.
Together, the combination targets both post-meal and fasting blood glucose levels, facilitating more comprehensive glycemic control.
Product Details
Brand Name: Stigamet DS Tablet
Generic Name: Sitagliptin 50mg + Metformin 1000mg
Therapeutic Class: DPP-4 Inhibitor + Biguanide (Dual Antidiabetic Combination)
Dosage Form: Film-Coated Tablet
Strength: Sitagliptin 50mg + Metformin 1000mg
Package Size: 14’s
Storage Condition: Store below 30 °C; keep dry, tightly closed in original blister/pack; protect from moisture.
Manufacturer: Caliph Pharma (Pvt.) Ltd.
FAQ
What is Stigamet DS Tablet used for?
It is used for managing type 2 diabetes in adults when diet and exercise alone are inadequate, by combining Sitagliptin and Metformin in a single tablet.
When should I take Stigamet DS Tablet?
Usually once a day with breakfast (or as directed by your doctor) to reduce side-effects and maintain stable blood sugar.
Can I stop taking other diabetes medicines when I start Stigamet DS Tablet?
Only under physician guidance. Your doctor will decide whether to replace, add or stop other medications.
What happens if I miss a dose?
Take the missed dose as soon as you remember if it’s not close to the time for the next dose. Do not double the dose.
Will this help reduce my HbA1c?
Yes — the combination helps control fasting and post-meal glucose, which contributes to HbA1c reduction when used with diet and exercise.
Additional information
| Generic Composition | Sitagliptin 50mg + Metformin 1000mg |
|---|---|
| Pack Size | 14`s |

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